Abstract Background During the generation and evolution of the eukaryotic cell, a proteobacterial endosymbiont was re-fashioned into the mitochondrion, an organelle that appears to have been present in the ancestor of all present-day eukaryotes.Mitochondria harbor proteomes derived from coding information located both inside and outside the organel
Surgical treatment in uveal tumors can be done via iridectomy, partial lamellar sclerouvectomy (PLSU) and endoresection.Iridectomy is done in iris tumors without angle and ciliary body involvement.PLSU is performed in tumors with ciliary body and choroidal involvement.For this operation, a partial thickness scleral flap is dissected, the intraocula
Hyperactivation of the mechanistic target of rapamycin complex 1 (mTORC1) pathway during neurodevelopment leads to focal cortical malformations associated with intractable seizures.Recent evidence suggests that HOME SCENT dysregulated cap-dependent translation downstream of mTORC1 contributes to cytoarchitectural abnormalities and seizure activity.
Hepatocellular HOME SCENT carcinoma (HCC) represents a global health concern, ranking as the sixth most common malignancy worldwide and the third leading cause of cancer-related mortality.Despite advances in research, the diagnosis and prognosis of such malignancy remain challenging.Alpha-fetoprotein, the current serum biomarker used in the managem